Overview
Publication
Stat Med. 2009 Feb 15; 28(4):716-9.
PubMed ID: 19140113
Title
Response to Andrew Dunning's comment on 'evaluating a surrogate endpoint at three levels, with application to vaccine development'
Authors
Gilbert PB, Qin L, Self SG
Abstract
In replying to Andrew Dunning’s helpful letter, we endeavor to clarify the value of incorporating baseline participant predictors of the potential surrogate endpoint and of the clinical endpoint into the evaluation of a surrogate endpoint. Such baseline predictors are useful for the evaluation of surrogates defined within each of the statistical and principal surrogate frameworks, which are complementary.
With the publicly available data in the CAVD DataSpace we can Learn about studies, products, assays, antibodies, and publications, Find subjects with common characteristics, Plot assay results across studies and years of research, and Compare monoclonal antibodies and their neutralization curves. Data are also accessible via DataSpaceR, our R API.
Sign in to see full information about this publication and to download study data when available.
Related Studies
No related studies