Overview
Publication
Curr Opin HIV AIDS. 2007 May; 2(3):169-76.
PubMed ID: 19372883
Title
Neutralizing and other antiviral antibodies in HIV-1 infection and vaccination
Authors
Montefiori DC, Morris L, Ferrari G, Mascola JR
Abstract
New findings continue to support the notion that broadly crossreactive neutralizing antibody induction is a worthwhile and achievable goal for HIV-1 vaccines. Immunogens are needed that can overcome the genetic variability and complex immune evasion tactics of the virus. Other antibodies might bridge innate and acquired immunity for possible beneficial vaccine effects. This review summarizes progress made over the past year that has enhanced our understanding of humoral immunity as it relates to HIV-1 vaccine development.
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