Overview
Publication
Curr Opin HIV AIDS. 2010 Sep; 5(5):397-403.
PubMed ID: 20978380
Title
Update on mucosal HIV vaccine vectors
Authors
Duerr A
Abstract
HIV's primary site of infection is at mucosal surfaces. To successfully defend against sexually transmitted diseases (STDs), including HIV, protection may need to be specifically elicited at the mucosal interface, where the organism enters the host. Recent advances in measuring adaptive responses at mucosal sites and optimization of techniques for low-dose repeated mucosal challenge in nonhuman primate animal models allow more in depth studies of mucosal vaccine vectors.
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