Overview
Publication
PLOS ONE. 2016 Aug 18; 11(8):e0160487.
PubMed ID: 27536938
Title
Transient peripheral immune activation follows elective sigmoidoscopy or circumcision in a cohort study of MSM at risk of HIV infection
Authors
Lama JR, Karuna ST, Grant SP, Swann EM, Ganoza C, Segura P, Montano SM, Lacherre M, De Rosa SC, Buchbinder S, Sanchez J, McElrath MJ, Lemos MP, for the HVTN 914 Study Team
Abstract
Rectal and genital sampling in HIV prevention trials permits assessments at the site of HIV entry. Yet the safety and acceptability of circumcision and sigmoidoscopy (and associated abstinence recommendations) are unknown in uncircumcised men who have sex with men (MSM) at high risk of HIV infection.
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