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Publications / Wagh 2023 (Curr Opin HIV AIDS)

Overview

Publication

Curr Opin HIV AIDS. 2023 Jul 01; 18(4):164-170.

PubMed ID: 37249911

Title

Divide and conquer: Broadly neutralizing antibody combinations for improved HIV-1 viral coverage

Authors

Wagh K, Seaman MS

Abstract

Successful HIV-1 prevention and therapy will require broad and potent coverage of within-host and global viral diversity. Broadly neutralizing antibody (bNAb) combination and multispecific therapeutics provide an opportunity to meet this challenge due to the complementary activity of individual antibody components. Here, we review the principles and applications of this concept.

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