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Publications / Anez 2023 (JAMA Netw Open)

Overview

Publication

JAMA Netw Open. 2023 Apr 03; 6(4):e239135.

PubMed ID: 37099299

Title

Safety, immunogenicity, and efficacy of the NVX-CoV2373 COVID-19 vaccine in adolescents: A randomized clinical trial

Authors

Anez G, Dunkle LM, Gay CL, Kotloff KL, Adelglass JM, Essink B, Campbell JD, Cloney-Clark S, Zhu M, Plested JS, Roychoudhury P, Greninger AL, Patel N, McGarry A, Woo W, Cho I, Glenn GM, Dubovsky F, 2019nCoV-301 – Pediatric Expansion Study Group

Abstract

Greater than 20% of cases and 0.4% of deaths from COVID-19 occur in children. Following demonstration of the safety and efficacy of the adjuvanted, recombinant spike protein vaccine NVX-CoV2373 in adults, the PREVENT-19 trial immediately expanded to adolescents.

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