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Publications / Garrett 2022 (Clin Infect Dis)

Overview

Publication

Clin Infect Dis. 2022 Aug 24; 75(1):e289-e292.

PubMed ID: 35353885

Title

High asymptomatic carriage with the omicron variant in South Africa

Authors

Garrett N, Tapley A, Andriesen J, Seocharan I, Fisher LH, Bunts L, Espy N, Wallis CL, Randhawa AK, Miner MD, Ketter N, Yacovone M, Goga A, Huang Y, Hural J, Kotze P, Bekker LG, Gray GE, Corey L, Ubuntu Study Team

Abstract

We report a 23% asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) Omicron carriage rate in participants being enrolled into a clinical trial in South Africa, 15-fold higher than in trials before Omicron. We also found lower CD4 + T-cell counts in persons with human immunodeficiency virus (HIV) strongly correlated with increased odds of being SARS-CoV-2 polymerase chain reaction (PCR) positive.

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