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Publications / Ochsenbauer 2009 (Curr Opin HIV AIDS)

Overview

Publication

Curr Opin HIV AIDS. 2009 Sep; 4(5):418-25.

PubMed ID: 20048706

Title

New virologic reagents for neutralizing antibody assays

Authors

Ochsenbauer C, Kappes JC

Abstract

This review summarizes current and novel virologic reagents employed for the development and application of in-vitro assays that assess neutralizing activity of antibodies against HIV-1. Characteristics of several virologic approaches are placed in context with various cellular targets and assay read-outs intended to determine potency and breadth of neutralization in patient cohorts and clinical vaccine trials.

With the publicly available data in the CAVD DataSpace we can Learn about studies, products, assays, antibodies, and publications, Find subjects with common characteristics, Plot assay results across studies and years of research, and Compare monoclonal antibodies and their neutralization curves. Data are also accessible via DataSpaceR, our R API.

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