Overview
Publication
Curr Opin HIV AIDS. 2009 Sep; 4(5):400-7.
PubMed ID: 20048704
Title
Impact of host cell variation on the neutralization of HIV-1 in vitro
Authors
Polonis VR, Schuitemaker H, Bunnik EM, Brown BK, Scarlatti G
Abstract
In this review we present current advances in our understanding of HIV-1 neutralization assays that employ primary cell types, as compared with those that utilize cell lines and the newer, more standardized pseudovirus assays. A commentary on the challenges of standardizing in-vitro neutralization assays using primary cells is included.
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