Overview
Publication
Curr Opin HIV AIDS. 2009 Sep; 4(5):347-51.
PubMed ID: 20048696
Title
Neutralizing antibodies against HIV-1: Can we elicit them with vaccines and how much do we need?
Authors
Montefiori DC, Mascola JR
Abstract
This review describes some of the major obstacles that have impeded progress in the development of an effective neutralizing antibody-based HIV-1 vaccine and explains why it may be possible to overcome these obstacles. A renewed interest in the B-cell response in HIV-1-infected individuals is emphasized.
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