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Publications / Haynes 2010 (Nat Struct Mol Biol)

Overview

Publication

Nat Struct Mol Biol. 2010 May; 17(5):543-5.

PubMed ID: 20442740

Title

HIV-1 autoreactive antibodies: Are they good or bad for HIV-1 prevention?

Authors

Haynes BF, Nicely NI, Alam SM

Abstract

A new crystal structure of an anti–HIV-1 envelope antibody bound to an envelope–receptor complex shows the antibody binding both the HIV-1 envelope and the CD4 receptor, raising the question of what the role of antibody autoreactivity in host responses to HIV-1 may be.

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