Overview
Publication
Gastroenterology. 2011 Feb; 140(2):686-696.e1.
PubMed ID: 20875418
Title
Spontaneous control of HCV is associated with expression of HLA-B 57 and preservation of targeted epitopes
Authors
Kim AY, Kuntzen T, Timm J, Nolan BE, Baca MA, Reyor LL, Berical AC, Feller AJ, Johnson KL, Schulze zur Wiesch J, Robbins GK, Chung RT, Walker BD, Carrington M, Allen TM, Lauer GM
Abstract
HLA class I alleles are linked to spontaneous control of hepatitis C virus (HCV) and human immunodeficiency virus-1, but for HCV the roles of particular alleles and corresponding CD8(+) T-cell responses remain incompletely defined. We aimed to determine the correlations between these alleles and natural outcomes of HCV and determine associated key T-cell responses.
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