Overview
Publication
Curr Opin HIV AIDS. 2013 Sep; 8(5):432-6.
PubMed ID: 23719202
Title
Sieve analysis in HIV-1 vaccine efficacy trials
Authors
Edlefsen PT, Gilbert PB, Rolland M
Abstract
The genetic characterization of HIV-1 breakthrough infections in vaccine and placebo recipients offers new ways to assess vaccine efficacy trials. Statistical and sequence analysis methods provide opportunities to mine the mechanisms behind the effect of an HIV vaccine.
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