Overview
Publication
Curr Opin HIV AIDS. 2014 May; 9(3):235-41.
PubMed ID: 24670319
Title
T follicular helper cells and HIV/SIV-specific antibody responses
Authors
Petrovas C, Koup RA
Abstract
Here, we describe recent data on the characterization of follicular helper CD4 T cells (Tfh) and the dynamics of Tfh-B-cell interactions in HIV and simian immunodeficiency virus (SIV) infection and discuss important aspects of these interactions that need to be addressed in order to design more effective vaccines that elicit broadly neutralizing antibodies.
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