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Publications / Eckels 2013 (BMC Bioinformatics)

Overview

Publication

BMC Bioinformatics. 2013 Apr 30; 14(NA):145.

PubMed ID: 23631706

Title

Quality control, analysis and secure sharing of Luminex immunoassay data using the open source LabKey Server platform

Authors

Eckels J, Nathe C, Nelson EK, Shoemaker SG, Nostrand EV, Yates NL, Ashley VC, Harris LJ, Bollenbeck M, Fong Y, Tomaras GD, Piehler B

Abstract

Immunoassays that employ multiplexed bead arrays produce high information content per sample. Such assays are now frequently used to evaluate humoral responses in clinical trials. Integrated software is needed for the analysis, quality control, and secure sharing of the high volume of data produced by such multiplexed assays. Software that facilitates data exchange and provides flexibility to perform customized analyses (including multiple curve fits and visualizations of assay performance over time) could increase scientists' capacity to use these immunoassays to evaluate human clinical trials.

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