Overview
Study information
| Network: | CAVD |
| Grant Affiliation: | Hu: Unmasking Conserved Epitopes |
| Strategy: | Combo: DNA, protein & vector vaccines |
| Study Type: | Pre-Clinical NHP |
| Species: | Rhesus macaque |
| Stage: | Assays Completed |
| Study Start Date: | 2014-10-23 |
| Study Made Public: | 2019-03-15 |
Title
NHP Immunogenicity Study of CD4i Env (MX2)
Description
CAVD 463 (MX2) is a non-human primate study to determine whether CD4-independent Envelopes [CD4i 89.6 (i.e i89.6 A2) and CD4i 89.6 N7 (i.e. i89.6 N7 D4T)] are more immunogenic than their parental counterparts [89.6 WT and 89.6 N7, respectively].
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Products
Alum DNA-SIV-Gag-Pol v-NY-89.6 WT Env gp160 v-NY-CD4i 89.6 Env gp160 (A2) v-NY-SIV gag/pol Env gp120 (89.6 N7) v-NY-Env gp160 (89.6 N7) Env gp120 (89.6 WT) v-NY-Env gp160 (i89.6 d4T) Env gp120 (i89.6 A2) Env gp120 (i89.6 d4T)Integrated data
BAMA, ICS, NAb
Non-integrated data
No non-integrated data is available for this study.