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Studies / CAVD 465

Overview

Study information

Network:CAVD
Grant Affiliation:Ɯberla: Antibodies without HIV T helper cells
Strategy:Combo: Vector & VLP vaccines
Study Type:Pre-Clinical NHP
Species:Rhesus macaque
Stage:Assays Completed
Study Start Date:2014-11-08
Study Made Public:2019-08-12

Title

Challenge virus-specific T helper cell responses induced by adenoviral vector prime VLP booster immunization regimens do not correlate with enhanced susceptibility to virus acquisition

Description

CAVD 465 is a non-human primate challenge study to evaluate and compare the immunogenicity of priming with adenoviral vectors encoding FIV Gag, SIV Gag, HIV Env or a control antigen (RSV-F) and boosting with VLPs containing FIV Gag and HIV Env (FIVHenv) or SIV Gag and HIV Env (SIVHenv).

Products

SHIV-SF162P3 Saline Ad-FIV Gag Ad-RSV-F Ad-SIV Gag/Pol Ad-Henv FIV Henv SIV Henv

Integrated data

BAMA, ICS, NAb

Non-integrated data

No non-integrated data is available for this study.