Overview
Study information
| Network: | CAVD |
| Grant Affiliation: | Überla: Antibodies without HIV T helper cells |
| Strategy: | Combo: Vector & VLP vaccines |
| Study Type: | Pre-Clinical NHP |
| Species: | Rhesus macaque |
| Stage: | Assays Completed |
| Study Start Date: | 2014-11-08 |
| Study Made Public: | 2019-08-12 |
Title
Challenge virus-specific T helper cell responses induced by adenoviral vector prime VLP booster immunization regimens do not correlate with enhanced susceptibility to virus acquisition
Description
CAVD 465 is a non-human primate challenge study to evaluate and compare the immunogenicity of priming with adenoviral vectors encoding FIV Gag, SIV Gag, HIV Env or a control antigen (RSV-F) and boosting with VLPs containing FIV Gag and HIV Env (FIVHenv) or SIV Gag and HIV Env (SIVHenv).
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Products
SHIV-SF162P3 Saline Ad-FIV Gag Ad-RSV-F Ad-SIV Gag/Pol Ad-Henv FIV Henv SIV HenvIntegrated data
BAMA, ICS, NAb
Non-integrated data
No non-integrated data is available for this study.