Overview
Study information
| Network: | CAVD |
| Grant Affiliation: | Hu: Unmasking Conserved Epitopes |
| Strategy: | Vector vaccines (viral or bacterial) |
| Study Type: | Pre-Clinical Non-NHP |
| Species: | Mouse |
| Stage: | Assays Completed |
| Study Start Date: | 2014-12-19 |
| Study Made Public: | 2015-06-19 |
Title
Study to determine whether Env immunogen binding to human CD4 affects immunogenicity - Mouse Immunogenicity Study 7 Revised (MU7R)
Description
CAVD 475 (MU7R) is a preclinical mouse study to determine whether the presence of huCD4 affects immunogenicity by comparing huCD4 transgenic mice versus BL/6 mice immunized with either 89.6 WT Env, CD4-independent Envelope containing a CD4 binding site [CD4i 89.6 N7 (D4T)], or CD4-independent Envelope lacking a CD4 binding site [CD4i 89.6 (A2)].
Sign in to see full information about this study and to download study data.
Products
v-NY-89.6 WT Env gp160 v-NY-CD4i 89.6 N7 Env gp160 (D4T) v-NY-CD4i 89.6 Env gp160 (A2) v-NY-SIV gag/polIntegrated data
No integrated data is available for this study.
Non-integrated data
No non-integrated data is available for this study.