Overview
Study information
| Network: | CAVD |
| Grant Affiliation: | Hu: Unmasking Conserved Epitopes |
| Strategy: | Combo: Protein & vector vaccines |
| Study Type: | Pre-Clinical Non-NHP |
| Species: | Mouse |
| Stage: | Assays Completed |
| Study Start Date: | 2015-03-11 |
| Study Made Public: | 2016-02-16 |
Title
Cytoplasmic tail modifications in HIV-1/JRFL Env can improve the Env-specific antibody response
Description
CAVD 483 (MU8) is a preclinical mouse study to demonstrate whether cytoplasmic tail mutations which increase cell surface expression of Env exhibit increased immunogenicity in a vaccinia prime/boost regimen.
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Products
v-NY-SIV gag/pol JRFL gp120 v-NY-Env (JRFL WT) v-NY-Env (JRFL TM1)Integrated data
NAb
Non-integrated data
No non-integrated data is available for this study.