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Studies / HVTN 505

Overview

Study information

Network:HVTN
Grant Affiliation:NA
Strategy:Combo: DNA & vector vaccines
Study Type:Phase II
Species:Human
Stage:Primary Analysis Complete
Study Start Date:2009-05-29
Study Made Public:NA

Title

Phase 2b, randomized, placebo-controlled test-of- concept trial to evaluate the safety and efficacy of a multiclade HIV-1 DNA plasmid vaccine followed by a multiclade HIV-1 recombinant adenoviral vector vaccine in HIV-uninfected, adenovirus type 5 neutralizing antibody negative, circumcised men and male-to-female (MTF) transgender persons, who have sex with men

Description

HVTN 505 is a Phase IIb clinical trial to evaluate the safety and immunogenicity of VRC-HIVDNA016-00-VP (DNA) and VRCHIVADV014-00-VP (rAd5).

Products

VRC-HIVDNA016-00-VP VRC-HIVADV014-00-VP VRC-PBSPLA043-00-VP VRC-DILUENT013-DIL VP

Integrated data

BAMA, ICS, NAb

Non-integrated data

ADCP, Demographics (Supplemental), Fc Array